LITAF Antibody
Catalog Number:
ASB-OACA07878
- Images (3)
| Article Name: | LITAF Antibody |
| Biozol Catalog Number: | ASB-OACA07878 |
| Supplier Catalog Number: | OACA07878 |
| Alternative Catalog Number: | ASB-OACA07878-100UL,ASB-OACA07878-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Lipopolysaccharide-induced tumor necrosis factor-alpha factor protein (1-161AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | lipopolysaccharide-induced TNF-alpha factor,lipopolysaccharide-induced tumor necrosis factor-alpha factor,LPS-induced TNF-alpha factor,p53-induced gene 7 protein,PIG7,SIMPLE,small integral membrane protein of lysosome/late endosome,TP53I7,tumor protein p53 inducible protein 7. |
| Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation (PubMed:23166352). Plays a role in targeting endocytosed EGFR and ERGG3 for lysosomal degradation, and thereby helps downregulate downstream signaling cascades (PubMed:23166352). Helps recruit the ESCRT complex components TSG101, HGS and STAM to cytoplasmic membranes (PubMed:23166352). Probably plays a role in regulating protein degradation via its interaction with NEDD4 (PubMed:15776429). May also contribute to the regulation of gene expression in the nucleus (PubMed:10200294, PubMed:15793005). Binds DNA (in vitro) and may play a synergistic role with STAT6 in the nucleus in regulating the expression of various cytokines (PubMed:15793005). May regulate the expression of numerous cytokines, such as TNF, CCL2, CCL5, CXCL1, IL1A and IL10 (PubMed:10200294, PubMed:15793005). |
| Clonality: | Polyclonal |
| NCBI: | 9516 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human thymus tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100 |
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Western blot All lanes: LITAFantibody at 1.91ug/ml+ Hela whole cell lysate Goat poly |
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