DDX20 Antibody
Catalog Number:
ASB-OACA07900
- Images (3)
| Article Name: | DDX20 Antibody |
| Biozol Catalog Number: | ASB-OACA07900 |
| Supplier Catalog Number: | OACA07900 |
| Alternative Catalog Number: | ASB-OACA07900-100UL,ASB-OACA07900-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Probable ATP-dependent RNA helicase DDX20 protein (25-280AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | component of gems 3,DEAD (Asp-Glu-Ala-Asp) box polypeptide 20,DEAD box protein 20,DEAD box protein DP 103,DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD,DEAD-box protein DP103,DP103,gemin-3,GEMIN3,probable ATP-dependent RNA helicase DDX20,SMN-interacting protein. |
| The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs). |
| Clonality: | Polyclonal |
| NCBI: | 11218 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100 |
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Western blot All lanes: ADDX20antibody at 1.91ug/ml Lane 1A: 293T whole cell lysate |
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