ZC3HC1 Antibody
Catalog Number:
ASB-OACA07933
- Images (3)
| Article Name: | ZC3HC1 Antibody |
| Biozol Catalog Number: | ASB-OACA07933 |
| Supplier Catalog Number: | OACA07933 |
| Alternative Catalog Number: | ASB-OACA07933-100UL,ASB-OACA07933-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Nuclear-interacting partner of ALK protein (1-260AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | hematopoietic stem/progenitor cell protein 216,HSPC216,NIPA,nuclear interacting partner of anaplastic lymphoma kinase (ALK),nuclear-interacting partner of ALK,Nuclear-interacting partner of anaplastic lymphoma kinase,Zinc finger C3HC-type protein 1. |
| Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events. |
| Clonality: | Polyclonal |
| NCBI: | 51530 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human prostata cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human skin tissue at dilution 1:100 |
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Western blot All lanes: ZC3HC1 antibody at 0.98ug/ml Lane 1: Hela whole cell lysate< |
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