MBTPS1 Antibody
Catalog Number:
ASB-OACA08076
- Images (3)
| Article Name: | MBTPS1 Antibody |
| Biozol Catalog Number: | ASB-OACA08076 |
| Supplier Catalog Number: | OACA08076 |
| Alternative Catalog Number: | ASB-OACA08076-100UL,ASB-OACA08076-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Membrane-bound transcription factor site-1 protease protein (803-1052AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | endopeptidase S1P,membrane-bound transcription factor site-1 protease,PCSK8,proprotein convertase subtilisin/kexin type 8,S1P,SEDKF,site-1 protease,SKI-1,subtilisin/kexin isozyme-1,Subtilisin/kexin-isozyme 1. |
| Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes. |
| Clonality: | Polyclonal |
| NCBI: | 8720 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human lung tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100 |
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Western blot All lanes: MBTPS1antibody at 4.06ug/ml+ Mouse kidney tissue Goat polycl |
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