CALCOCO1 Antibody
Catalog Number:
ASB-OACA08431
- Images (3)
| Article Name: | CALCOCO1 Antibody |
| Biozol Catalog Number: | ASB-OACA08431 |
| Supplier Catalog Number: | OACA08431 |
| Alternative Catalog Number: | ASB-OACA08431-100UL,ASB-OACA08431-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Calcium-binding and coiled-coil domain-containing protein 1 protein (462-691AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | calcium-binding and coiled-coil domain-containing protein 1,calphoglin,Cocoa,coiled-coil coactivator protein,coiled-coil leucine zipper coactivator 1,inorganic pyrophosphatase activator,PP13275,sarcoma antigen NY-SAR-3. |
| Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity). In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). |
| Clonality: | Polyclonal |
| NCBI: | 57658 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100 |
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Western blot All lanes: ACALCOCO1antibody at 1.61ug/ml Lane 1A: 293T whole cell lys |
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