LFNG Antibody

Catalog Number: ASB-OACA08458
Article Name: LFNG Antibody
Biozol Catalog Number: ASB-OACA08458
Supplier Catalog Number: OACA08458
Alternative Catalog Number: ASB-OACA08458-100UL,ASB-OACA08458-50UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IHC, WB
Species Reactivity: Human, Mouse
Immunogen: Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe protein (1-250AA)
Conjugation: Unconjugated
Alternative Names: beta-1,3-N-acetylglucosaminyltransferase lunatic fringe,O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,SCDO3.
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity). Decreases the binding of JAG1 to NOTCH2 but not that of DLL1 (PubMed:11346656). Essential mediator of somite segmentation and patterning (By similarity).
Clonality: Polyclonal
NCBI: 3955
Form: Liquid
Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
Western blot
All lanes: ALFNGantibody at 4.43ug/ml
Lane 1A: Mouse spleen ti