Recombinant protein encompassing a sequence within the center region of human GART. The exact sequence is proprietary.
Alternative Names:
AIRS, GARS, PAIS, PGFT, PRGS, GARTF
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
