Recombinant protein encompassing a sequence within the center region of human HSD17B3. The exact sequence is proprietary.
Alternative Names:
EDH17B3, SDR12C2
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
