Recombinant protein encompassing a sequence within the center region of human STXBP2. The exact sequence is proprietary.
Alternative Names:
FHL5, UNC18B, Hunc18b, UNC18-2, pp10122, MUNC18-2
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
