UNC13D Antibody - N-terminal region

Catalog Number: ASB-OAGA05603
Article Name: UNC13D Antibody - N-terminal region
Biozol Catalog Number: ASB-OAGA05603
Supplier Catalog Number: OAGA05603
Alternative Catalog Number: ASB-OAGA05603-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Munc 13-4. The exact sequence is proprietary.
Alternative Names: FHL3, HLH3, HPLH3, Munc13-4
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Clonality: Polyclonal
Concentration: 1 mg/ml
NCBI: 201294
Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Form: Liquid
Sample (30 ug of whole cell lysate)
A: A431
5% SDS PAGE
diluted at 1:1000
Sample (50 ug of whole cell lysate)
A: mouse lung
5% SDS PAGE
diluted at 1:500