Recombinant protein encompassing a sequence within the center region of human Nek1. The exact sequence is proprietary.
Alternative Names:
ALS24, SRPS2, SRTD6, SRPS2A, NY-REN-55
The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.