Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)
Alternative Names:
Integrin alpha-5 (CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain, Integrin alpha-5 light chain]
function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarc