Synthesized peptide derived from human NOTCH1 (Cleaved-Val1711)
Alternative Names:
Neurogenic locus notch homolog protein 1 (Notch 1, hN1, Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation, Notch 1 intracellular domain (NICD)]
disease:Defects in NOTCH1 are a cause of aortic valve disease [MIM:109730]. The disorder consists of an early developmental defect in the aortic valve and a later de-repression of calcium deposition that causes progressive aortic valve disease. Calcifica
