Eosin-5-maleimide is a good photosensitizer and can be used to selectively label thiols. It has a quantum yield of 0.57 for singlet oxygen generation, which makes it useful for photoconversion of electron-rich materials such as diaminobenzidine (DAB) or fluorescent dyes into highly electron-dense materials for high resolution electron microscopy studies. Additionally, eosin is a good fluorescence acceptor for fluorescein (FAM), dansyl and coumarin dyes in fluorescence resonance energy transfer (FRET). &lamba,Ex/&lamba,Em (MeOH) = 524/545 nm epsilon = 100,000 Orange solid soluble in DMF or DMSO Store at -20C and protect from light C24H9Br4NO7 MW: 742.95
Source:
Synthetic
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