C11orf23, Chromosome 11 open reading frame 23, KIAA1558, PP6R3, PP6R3_HUMAN, PPP6R3, Protein phosphatase 6 regulatory subunit 3, SAP190, SAPL, SAPLa, SAPS domain family member 3, SAPS domain family, member 3, Serine/threonine-protein phosphatase 6 regulatory subunit 3, Sporulation induced transcript 4 associated protein SAPL, Sporulation-induced transcript 4-associated protein SAPL.
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C, MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]
