Nucleolar protein 3 Polyclonal Antibody, APC-Cy7 Conjugated, APC/Cy7, Rabbit
Biozol Catalog Number:
BSS-BS-7080R-APC-CY7
Supplier Catalog Number:
bs-7080R-APC-Cy7
Alternative Catalog Number:
BSS-BS-7080R-APC-CY7-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF
Species Reactivity:
Mouse
Conjugation:
APC/Cy7
Alternative Names:
Apoptosis repressor with CARD, ARC, Muscle enriched cytoplasmic protein, MYC, Myp, NOP, Nop30, Nucleolar protein 3 apoptosis repressor with CARD domain, Nucleolar protein 3, Nucleolar protein of 30 kDa, NOL3_MOUSE .
Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD)bcontaining molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf 1, caspase 9 and caspase 2. Apoptosis repressor with CARD is a CARD domain containing protein that interacts with caspase 2 and 8 to inhibit enzymatic activity of caspase 8. Apoptosis repressor with CARD suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR 1, and DR3. The mRNA of Apoptosis repressor with CARD is primarily expressed in skeletal muscle and cardiac tissue. The nuclear isoform (1/Nop30) may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis.
