C22orf31/HS747E2A Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-9073R-PE
Supplier Catalog Number:
bs-9073R-PE
Alternative Catalog Number:
BSS-BS-9073R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF, WB
Species Reactivity:
Human
Conjugation:
PE
Alternative Names:
HS747E2A, bK747E2.1, C22orf31, Chromosome 22 open reading frame 31, HS747E2A, Hypothetical protein LOC25770, CV031_HUMAN.
C22orf31, also known as HS747E2A or bK747E2.1, is a 290 amino acid protein encoded by a gene located on human chromosome 22, which contains over 500 genes and about 49 million bases. As the second smallest human chromosome, chomosome 22 contains a wide variety of genes with numerous functions. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.
