This is a mouse antibody that specifically recognizes PfCSP. The clone 850 binds to NANP repeats with high affinity and achieves potent parasite inhibition. The clone 850 is one of the highest affinity NANP binders described to date, with KD of 1 nM, 25 pM, and 32 pM for NPNA3 and NANP6 peptides and recombinant full-length PfCSP, respectively. The clone 850 was isolated following immunization with an antigen containing PfCSP repeats in a transgenic mouse model.
* VAT and and shipping costs not included. Errors and price changes excepted