Recombinant Human Anti-MAPT Antibody (clone Tilavonemab) Preis auf Anfrage
Catalog Number:
CRB-VS-0923-FY255-1
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| Article Name: | Recombinant Human Anti-MAPT Antibody (clone Tilavonemab) Preis auf Anfrage |
| Biozol Catalog Number: | CRB-VS-0923-FY255-1 |
| Supplier Catalog Number: | VS-0923-FY255 |
| Alternative Catalog Number: | CRB-VS-0923-FY255-1 |
| Manufacturer: | Creative Biolabs |
| Category: | Antikörper |
| Tilavonemab is a humanized IgG4 antibody that was developed by C2N Diagnostics and AbbVie to treat tauopathies. It specifically targets an aggregated, extracellular form of pathological tau by binding to amino acids 25-30 in taus N-terminus. By blocking the uptake of tau aggregates in human and mouse neurons, Tilavonemab effectively reduces brain atrophy. This particular form of tau is believed to play a role in the transneuronal propagation of tau pathology in cell-based and mouse models, potentially explaining the characteristic progression of tau pathology in Alzheimers disease. |
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