CD45 Mouse Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMM85077
Article Name: CD45 Mouse Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMM85077
Supplier Catalog Number: AMM85077
Alternative Catalog Number: EKL-AMM85077-50UL,EKL-AMM85077-100UL
Manufacturer: EnkiLife
Host: Mouse
Category: Antikörper
Application: ICC, IHC, WB
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: GP180, L CA, CD45 antigen
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
Clonality: Monoclonal
Molecular Weight: Calculated MW: 145 kDa, Observed MW: 145 kDa
NCBI: 19264
UniProt: P08575
Buffer: Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Purity: Affinity Purification
Form: Liquid
Target: CD45
Application Dilute: WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200