Chk2 Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE01822
Article Name: Chk2 Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE01822
Supplier Catalog Number: AMRe01822
Alternative Catalog Number: EKL-AMRE01822-50UL, EKL-AMRE01822-100UL, EKL-AMRE01822-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: ICC, IP, WB
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: CHEK2, CDS1, CHK2, RAD53, Serine/threonine-protein kinase Chk2, CHK2 checkpoint homolog, Cds1 homolog, Hucds1, hCds1, Checkpoint kinase 2
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Clonality: Monoclonal
Molecular Weight: Calculated MW: 61 kDa, Observed MW: 61 kDa
NCBI: 11200
UniProt: O96017
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purity: Affinity Purification
Form: Liquid
Target: CHEK2
Application Dilute: WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50