Chk2 Rabbit Monoclonal Antibody, Unconjugated
Catalog Number:
EKL-AMRE01822
Product Overview
Article Name:
Chk2 Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE01822
Supplier Catalog Number:
AMRe01822
Alternative Catalog Number:
EKL-AMRE01822-50UL, EKL-AMRE01822-100UL, EKL-AMRE01822-200UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
ICC, IP, WB
Species Reactivity:
Human
Conjugation:
Unconjugated
Alternative Names:
CHEK2, CDS1, CHK2, RAD53, Serine/threonine-protein kinase Chk2, CHK2 checkpoint homolog, Cds1 homolog, Hucds1, hCds1, Checkpoint kinase 2
Product Description
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Product Properties
Clonality:
Monoclonal
Molecular Weight:
Calculated MW: 61 kDa, Observed MW: 61 kDa
NCBI:
11200
UniProt:
O96017
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purity:
Affinity Purification
Form:
Liquid
Target:
CHEK2
Application Notes
Application Dilute:
WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50