Phospho-ErbB3 (Y1222) (11E17) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE05900
Article Name: Phospho-ErbB3 (Y1222) (11E17) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE05900
Supplier Catalog Number: AMRe05900
Alternative Catalog Number: EKL-AMRE05900-50UL, EKL-AMRE05900-100UL, EKL-AMRE05900-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: ERBB3, HER3, LCCS2, p180 ErbB3, p45 sErbB3, p85 sErbB3,
Binds and is activated by neuregulins and NTAK. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908).
Clonality: Monoclonal
Molecular Weight: 148kDa
NCBI: 2065
UniProt: P21860
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: ERBB3
Application Dilute: WB 1:1000-1:5000