Phospho-SIRT1 (T530) (4C14) Rabbit Monoclonal Antibody, Unconjugated
Catalog Number:
EKL-AMRE06007
Product Overview
Article Name:
Phospho-SIRT1 (T530) (4C14) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE06007
Supplier Catalog Number:
AMRe06007
Alternative Catalog Number:
EKL-AMRE06007-50UL, EKL-AMRE06007-100UL, EKL-AMRE06007-200UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Conjugation:
Unconjugated
Alternative Names:
NAD-dependent protein deacetylase sirtuin-1, hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SirtT1 75 kDa fragment, 75SirT1, SIRT1, SIR2L1,
Product Description
The Silent Information Regulator (SIR2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT1 deacetylase activity is inhibited by nicotinamide and activated by resveratrol. NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523, PubMed: 12006491, PubMed: 14976264, PubMed: 14980222, PubMed: 15126506, PubMed: 15152190, PubMed: 15205477, PubMed: 15469825, PubMed: 15692560, PubMed: 16079181, PubMed: 16166628, PubMed: 16892051, PubMed: 16998810, PubMed: 17283066, PubMed: 17290224, PubMed: 17334224, PubMed: 17505061, PubMed: 17612497, PubMed: 17620057, PubMed: 17936707, PubMed: 18203716, PubMed: 18296641, PubMed: 18662546, PubMed: 18687677, PubMed: 19188449, PubMed: 19220062, PubMed: 19364925, PubMed: 19690166, PubMed: 19934257, PubMed: 20097625, PubMed: 20100829, PubMed: 20203304, PubMed: 20375098, PubMed: 20620956, PubMed: 20670893, PubMed: 20817729, PubMed: 20955178, PubMed: 21149730, PubMed:
Product Properties
Clonality:
Monoclonal
Molecular Weight:
82kDa
NCBI:
23411
UniProt:
Q96EB6
Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity:
Affinity purification
Form:
Liquid
Target:
SIRT1
Application Notes
Application Dilute:
WB 1:1000-1:5000
