ADA (11N15) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE06574
Article Name: ADA (11N15) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE06574
Supplier Catalog Number: AMRe06574
Alternative Catalog Number: EKL-AMRE06574-50UL, EKL-AMRE06574-100UL, EKL-AMRE06574-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Rat
Conjugation: Unconjugated
Alternative Names: ada, ADA1,
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine (PubMed:8452534, PubMed:16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4 (PubMed:20959412). Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (PubMed:11772392). Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion (By similarity). Enhances CD4+ T-cell differentiation and proliferation (PubMed:20959412). Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change (PubMed:23193172). Stimulates plasminogen activation (PubMed:15016824). Plays a role in male fertility (PubMed:21919946, PubMed:26166670). Plays a protective role in early postimplantation embryonic development (By similarity).
Clonality: Monoclonal
Molecular Weight: 41kDa
NCBI: 100
UniProt: P00813
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: ADA
Application Dilute: WB 1:1000-1:5000



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