ADIPOR1 (12R16) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE06636
Article Name: ADIPOR1 (12R16) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE06636
Supplier Catalog Number: AMRe06636
Alternative Catalog Number: EKL-AMRE06636-50UL, EKL-AMRE06636-100UL, EKL-AMRE06636-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: FC, ICC, IHC, WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: Adiponectin receptor protein 1, Progestin and adipoQ receptor family member I , CGI-45, PAQR1, ADIPOR1,
Regulate fatty acid oxidation and the uptake of glucose by adiponectin. Each receptor activates a unique set of signaling molecules including AMPK, p38 MAPK and PPAR?. AdipoR1 has a high-affinity for globular adiponectin and low-affinity for full-length adiponectin, while AdipoR2 has an intermediate affinity for both forms. Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).
Clonality: Monoclonal
Molecular Weight: 43kDa
NCBI: 51094
UniProt: Q96A54
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: ADIPOR1
Application Dilute: WB 1:1000-1:5000,IHC 1:20-1:200,ICC/IF 1:50-1:200,FC 1:20-1:200



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