CBX4 (10P4) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE08056
Article Name: CBX4 (10P4) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE08056
Supplier Catalog Number: AMRe08056
Alternative Catalog Number: EKL-AMRE08056-50UL, EKL-AMRE08056-100UL, EKL-AMRE08056-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: FC, IF, IHC, IP, WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: CBX4, hPc2, NBP16, PC2,
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I (PubMed:12679040). Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131 (PubMed:22825850).
Clonality: Monoclonal
Molecular Weight: 61kDa
NCBI: 8535
UniProt: O00257
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: CBX4
Application Dilute: WB 1:500-1:2000,IHC 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50,IF-P 1:100-1:200



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