CD10 (15I14) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE08178
Article Name: CD10 (15I14) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE08178
Supplier Catalog Number: AMRe08178
Alternative Catalog Number: EKL-AMRE08178-50UL, EKL-AMRE08178-100UL, EKL-AMRE08178-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: ICC, IHC, IP, WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: Atriopeptidase, CALLA, CD10, CD10 antigen,Enkephalinase, EPN, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10), CALLA CD10, NEP, Neprilysin, Neutral endopeptidase,
CD10 is a transmembrane type II molecule and functions as a metallo-peptidase requiring zinc. Specifically, CD10 cleaves 1-3 amino-terminal amino acids from peptides with a preference for neutral amino acids (valine, iso-leucine, phenylalanine, leucine or alanine). Involved in the degradation of atrial natriuretic factor (ANF). Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1- 32)) (PubMed:2531377, PubMed:2972276, PubMed:16254193). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).
Clonality: Monoclonal
Molecular Weight: 86kDa
NCBI: 4311
UniProt: P08473
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: MME
Application Dilute: WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:20-1:50,IP 1:20-1:50



* VAT and and shipping costs not included.
Errors and price changes excepted
Availability
ORDER BY EMAIL
Product Guarantee and Expert Support
BIOZOL