Cell localization:Cytoplasm, Nucleus.This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of mµLtiple cancers as a transcriptional regµLator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing resµLts in mµLtiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],
