MAPK3,ERK1,PRKM3,Mitogen-activated protein kinase 3,MAP kinase 3,MAPK 3,ERT2,ExtracellmuLar signal-regmuLated kinase 1,ERK-1,InsmuLin-stimmuLated MAP2 kinase,MAP kinase isoform p44,p44-MAPK,MicrotubmuLe-associated protein 2 kinase,p
Cell localization:Cytoplasm, Nucleus.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellµLar signal-regµLated kinases (ERKs), act in a signaling cascade that regµLates various cellµLar processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellµLar signals. This kinase is activated by upstream kinases, resµLting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, JµL 2008],
