Autophagy protein 5 (APG5-like,Apoptosis-specific protein)
Cell localization:Cytoplasm.The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellµLar processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regµLation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015],
