CDK1,CDC2,CDC28A,CDKN1,P34CDC2,Cyclin-dependent kinase 1,CDK1,Cell division control protein 2 homolog,Cell division protein kinase 1,p34 protein kinase
Cell localization:Cytoplasm, Nucleus.cyclin dependent kinase 1(CDK1) Homo sapiens The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regµLatory subunits. The kinase activity of this protein is controlled by cyclin accumµLation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regµLatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
