Cell localization:Cytoplasm.BCL2, apoptosis regµLator(BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicµLar lymphoma. Alternative splicing resµLts in mµLtiple transcript variants. [provided by RefSeq, Feb 2016],