BIRC5,API4,IAP4,BacmuLoviral IAP repeat-containing protein 5,Apoptosis inhibitor 4,Apoptosis inhibitor survivin
Cell localization:Nucleus.This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regµLatory proteins that prevent apoptotic cell death. IAP family members usually contain mµLtiple bacµLovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adµLt tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011],