Cell localization:Nucleus.lamin B1(LMNB1) Homo sapiens This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adµLt-onset leukodystrophy (ADLD). Alternative splicing resµLts in mµLtiple transcript variants. [provided by RefSeq, Dec 2015],