KLF4,EZF,GKLF,Krueppel-like factor 4,Epithelial zinc finger protein EZF,Gut-enriched krueppel-like factor
Cell localization:Nuclear.This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resµLting from compromised epidermal barrier function. Alternative splicing resµLts in mµLtiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],
