p16 Arc, ARPC5, ARC16, Arp2/3 protein complex subunit p16,,p16 ARC
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
