Zonula occludens protein 3 Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE87576
Supplier Catalog Number:
AMRe87576
Alternative Catalog Number:
EKL-AMRE87576-50UL,EKL-AMRE87576-100UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Rat
Conjugation:
Unconjugated
Alternative Names:
ZO3, ZO-3
The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]
