Protein NDRG1, Differentiation-Related Gene 1 Protein, DRG-1, N-myc Downstream-Regulated Gene 1 Protein, Nickel-Specific Induction Protein Cap43, Reducing Agents and Tunicamycin-Responsive Protein, RTP, Rit42, NDRG1, CAP43, DRG1, RTP
Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the alpha/beta Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression, overexpression of NDRG1 is connected to malignant status of esophageal cancer.
Greater than 95% as determined by reducing SDS-PAGE
Application Notes:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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