Non-biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-HM4V6)
Biozol Catalog Number:
KAB-ITG-HM4V6
Supplier Catalog Number:
ITG-HM4V6
Alternative Catalog Number:
KAB-ITG-HM4V6-100UG, KAB-ITG-HM4V6-500UG
Manufacturer:
KactusBio
Category:
Proteine/Peptide
Species Reactivity:
Human
Alternative Names:
alphaVbeta6, Integrin alpha V beta 6, ITGAV&ITGB6,Integrin alpha V beta 6
Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus of ITGAV.It contains Phe31-Val992(ITGAV) acidic tail and Gly22-Asn707(ITGB6) basic tail.
Molecular Weight:
The protein has a predicted MW of 114 kDa (ITGAV)&79.1 kDa (ITGB6). Due to glycosylation, the protein migrates to 90-150 kDa based on Bis-Tris PAGE result.
Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Expression System:
HEK293
Purity:
> 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
Form:
Lyophilized
Sequence:
Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail
Target:
Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer
Human ITGAV&ITGB6 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
Immobilized Human ITGAV&ITGB6, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His Tag with the EC50 of 63.3 ng/ml determined by ELISA (QC Test).
Immobilized Human ITGAV&ITGB6, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB6 Antibody, hFc Tag with the EC50 of 6.0ng/ml determined by ELISA.
Immobilized Human ITGAV&ITGB6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGAV&ITGB6 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA.
Loaded Anti-ITGAV&ITGB6 Antibody, hFc Tag on ProA-Biosensor can bind Human ITGAV&ITGB6, His Tag with an affinity constant of 18.20 nM as determined in BLI assay (Gator Prime).
Loaded Anti-ITGB6 Antibody, hFc Tag on ProA-Biosensor can bind Human ITGAV&ITGB6, His Tag with an affinity constant of 92 nM as determined in BLI assay (Gator Prime).
Immobilized Human ITGAV&ITGB6, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGAV Antibody, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA.
The purity of Human ITGAV&ITGB6 is greater than 95% as determined by SEC-HPLC.
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