Human LRP-6 Protein (LRP-HM316)

Catalog Number: KAB-LRP-HM316
Article Name: Human LRP-6 Protein (LRP-HM316)
Biozol Catalog Number: KAB-LRP-HM316
Supplier Catalog Number: LRP-HM316
Alternative Catalog Number: KAB-LRP-HM316-100UG, KAB-LRP-HM316-500UG
Manufacturer: KactusBio
Category: Proteine/Peptide
Species Reactivity: Human
Alternative Names: LRP-6, DCAD2, FLJ90062, FLJ90421,LRP6
Recombinant Human LRP-6 Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Ala20-Pro630.
Molecular Weight: The protein has a predicted MW of 95.32 kDa. Due to glycosylation, the protein migrates to 97-110 kDa based on Bis-Tris PAGE result.
Tag: C-mFc
UniProt: O75581
Buffer: Supplied as 0.22 µm filtered solution in PBS (pH 7.4).
Expression System: HEK293
Purity: > 90% as determined by Bis-Tris PAGE
Form: Liquid
Sequence: Ala20-Pro630
Target: LRP-6
Human LRP-6 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
Immobilized Human LRP-6, mFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human R spondin 1, His Tag with the EC50 of 4.4ug/ml determined by ELISA.
Immobilized Human SOST, His Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 18.6ng/ml determined by ELISA.
Immobilized Human DKK1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 1.03ug/ml determined by ELISA (QC Test).
Loaded Human R spondin 1, His Tag on Anti-His-Biosensor can bind Human LRP-6, mFc Tag with an affinity constant of 8.97 nM as determined in BLI assay (Gator Prime).