Human PD-1/PDCD1 Protein (PD1-HM201)
Catalog Number:
KAB-PD1-HM201
- Images (7)
| Article Name: | Human PD-1/PDCD1 Protein (PD1-HM201) |
| Biozol Catalog Number: | KAB-PD1-HM201 |
| Supplier Catalog Number: | PD1-HM201 |
| Alternative Catalog Number: | KAB-PD1-HM201-100UG, KAB-PD1-HM201-500UG |
| Manufacturer: | KactusBio |
| Category: | Proteine/Peptide |
| Species Reactivity: | Human |
| Alternative Names: | PDCD1, PD1, CD279, SLEB2, PD-1 |
| Recombinant Human PD-1/PDCD1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu25-Gln167. |
| Molecular Weight: | The protein has a predicted MW of 42.6 kDa. Due to glycosylation, the protein migrates to 65-72 kDa based on Bis-Tris PAGE result. |
| Tag: | C-hFc (IgG1) |
| UniProt: | Q15116 |
| Buffer: | Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Expression System: | HEK293 |
| Purity: | > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC |
| Form: | Lyophilized |
| Sequence: | Leu25-Gln167 |
| Target: | PD-1/PDCD1 |
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Human PD-1 on Bis-Tris PAGE under reduced. The purity is greater than 95%. |
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Human PD-1, hFc Tag captured on CM5 Chip via Protein A can bind Biotinylated Human PD-L2, His-Avi Tag with an affinity constant of 0.344 uM as determined in SPR assay (Biacore T200). |
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The purity of Human PD-1 is greater than 95% as determined by SEC-HPLC. |
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Immobilized Human PD-1, hFc Tag at 0.5ug/ml (100ul/Well). Dose response curve for Biotinylated Anti-PD1 Antibody, hFc Tag with the EC50 of 14.6ng/ml determined by ELISA. |
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Immobilized Human PD-L1, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human PD-1, hFc Tag with the EC50 of 90.5ng/ml determined by ELISA (QC Test). |
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Human PD-1, hFc Tag captured on CM5 Chip via Protein A can bind Human PD-L1, His Tag with an affinity constant of 0.25 µM as determined in SPR assay (Biacore T200). |
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Serial dilutions of Anti-PD-1 Antibody were added into Human PD-1, hFc Tag: Biotinylated Human PD-L1, His Avi Tag binding reaction. The half maximal inhibitiory concentration (IC50) is 0.22ug/ml. |
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