Br-PBTC is a potent, 2/4 subtype-selective positive allosteric modulator of nAChRs (nicotinic acetylcholine receptors) with alpha2beta2, alpha2beta4, alpha4beta2, alpha4beta4, (alpha4beta2)2alpha4 and (alpha4beta2)2beta2 EC50 ranges from 0.1-0.6 µM. Br-PBTC acts from the c-tail of an alpha subunit[1].
Molecular Weight:
339.25
Purity:
98
CAS Number:
[1839519-57-1]
Formula:
C14H15BrN2OS
Target:
nAChR
Application Notes:
MCE Product type: Reference compound1
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