trans-J-113863 is a potent chemokine CCR1 and CCR3 receptor antagonist, and inhibits MIP-1alpha-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants with IC50s of 9.57 and 93.8 nM,respectively[1][2].
Molecular Weight:
655.44
CAS Number:
[202796-42-7]
Formula:
C30H37Cl2IN2O2
Target:
CCR
Application Notes:
MCE Product type: Reference compound1
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