SN003 is a reversible antagonist of corticotropin releasing factor receptor 1 (CRFR 1) (IC50 = 241 nM) that displays more than 1000-fold selectivity over CRFR 2. SN003 suppresses CRF-induced ACTH release in vitro. SN003 attenuates depressive-like behavior in rat[1][2][3].
Molecular Weight:
355.43
CAS Number:
[197801-88-0]
Formula:
C19H25N5O2
Target:
CRFR
Application Notes:
MCE Product type: Reference compound1
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