Nanaomycin A is the first selective DNMT3B inhibitor with an IC50 of 500 nM. Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells[1]. Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum with an IC80 value of 33.1 nM[2].
Molecular Weight:
302.28
Purity:
98.18
CAS Number:
[52934-83-5]
Formula:
C16H14O6
Target:
Antibiotic,DNA Methyltransferase,Parasite
Application Notes:
MCE Product type: Reference compound
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