8-Chloroadenosine (8-Cl-Ado), a unique ribonucleoside analog, depletes endogenous ATP that subsequently induces the phosphorylation and activation of AMPK. 8-Chloroadenosine induces autophagic cell death. 8-Chloroadenosine effectively inhibited in vivo tumor growth in mice[1].
Molecular Weight:
301.69
Purity:
99.75
CAS Number:
[34408-14-5]
Formula:
C10H12ClN5O4
Target:
AMPK,Autophagy,Nucleoside Antimetabolite/Analog
Application Notes:
MCE Product type: Reference compound
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