GS-441524 hydrochloride is a potent, orally active and CNS-penetrant viral RNA-dependent RNA polymerase inhibitor. GS-441524 hydrochloride competes with natural nucleosides to block viral RNA transcription as an alternative substrate and RNA chain terminator. GS-441524 hydrochloride inhibits the replication of feline infectious peritonitis virus, African swine fever virus, and severe acute respiratory syndrome coronavirus 2. GS-441524 hydrochloride reduces viral RNA levels in cats. GS-441524 hydrochloride can be used in research related to feline infectious peritonitis, African swine fever, and coronavirus disease 2019 (COVID-19)[1][2][3][4][5].
Molecular Weight:
327.72
Purity:
99.62
CAS Number:
[2378280-82-9]
Formula:
C12H14ClN5O4
Target:
DNA/RNA Synthesis,SARS-CoV
Application Notes:
MCE Product type: Reference compound
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