AMSH is a zinc metalloprotease that selectively cleaves Lys-63-linked polyubiquitin chains, but not Lys-48-linked chains. It plays a critical regulatory role in signaling in IL-2 and GM-CSF mediated pathways, acting as a positive BMP signaling modulator against SMAD6 and SMAD7 inhibition. AMSH Protein, Human is the recombinant human-derived AMSH protein, expressed by E. coli , with tag free.
Formula:
10617(Gene_ID)O95630 (S2-R424)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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