AMSHLP is a zinc metalloprotease that selectively cleaves Lys-63 linked polyubiquitin chains and acts as a positive regulator of the TORC1 signaling pathway. It specifically deubiquitinates SESN2, disrupts its interaction with the GATOR2 complex and inhibits SESN2-mediated regulation of TORC1. AMSH-LP Protein, Human (His) is the recombinant human-derived AMSHLP protein, expressed by E. coli , with N-6*His labeled tag.
Formula:
57559(Gene_ID)Q96FJ0 (D2-R436)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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