Recombinant fragment (around aa1400-1685) of human COL4A protein (exact sequence is proprietary)
Alternative Names:
Collagen alpha-5(IV) chain, COL4A5
Type IV collagen is the major structural component of the glomerular basement membrane (GBM), forming a hexagonal network together with lamins, proteoglycans, and nestin. Deletions of the N-terminal regions of COL4A5 and COL4A6 were found in Xq22.3 chromosome deletion syndrome and were located in an end-to-end manner. This results in a phenotype characteristic of diffuse leiomyomatosis and Alport syndrome (DL-ATS).
200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human pancreas stained with COL4A5 Recombinant Rabbit Monoclonal Antibody (COL4A5/9396R). Inset: PBS instead of primary antibody, secondary only negative control.
SDS-PAGE Analysis of Purified COL4A5 Recombinant Rabbit Monoclonal (COL4A5/9396R). Confirmation of Purity and Integrity of Antibody.
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